Role of C-type Natriuretic Peptide in Linear Growth

The role of C-type natriuretic peptide in cardiovascular medicine.

0195-668X/01/120997+11 $35.00/0 conventional drug therapy, in order to reduce plasma aminoterminal BNP levels, resulted in reduced total cardiovascular events when compared to therapy directed by clinical acumen. Much less is known about C-type natriuretic peptide (CNP) which was first isolated from porcine brain in 1990. It is now known that CNP has a much wider distribution and of particular ...

Urinary C-Type Natriuretic Peptide

Cardiorenal Research La , Rochester, Minnesota; a innesota. This work was O1 HL36634 and PO1 H tional Research (grant no lingham, Ms. Heublein, D the use of urinary C-type hey have no relationships pt received November 13 cepted December 5, 2012 his study was conducted to determine whether urinary excretion of C-type natriuretic peptide (CNP) is elevated in acute decompensated heart failure (AD...

Regulation of C-type natriuretic peptide expression.

C-type natriuretic peptide (CNP) is a member of the small family of natriuretic peptides that also includes atrial natriuretic peptide (ANP) and brain, or B-type natriuretic peptide (BNP). Unlike them, it performs its major functions in an autocrine or paracrine manner. Those functions, mediated through binding to the membrane guanylyl cyclase natriuretic peptide receptor B (NPR-B), or by signa...

C-type natriuretic peptide and vascular remodeling.

N-terminal pro-C-type natriuretic peptide, but not C-type natriuretic peptide, is greatly elevated in the fetal circulation.

We have identified recently a new peptide, NT-proCNP(1-50) (N-terminal pro-C-type natriuretic peptide), in the circulation of humans and sheep. A previous report of an elevated fetal-maternal gradient in immunoreactive CNP raised the possibility that processing and metabolism of proCNP may differ in maternal and fetal tissues. We therefore collected matching peripheral maternal and umbilical co...